The Germantown Fire Department operates at the Paramedic Level Service. With this service, Paramedics are able to administer lifesaving medications, along with performing lifesaving interventions prior to transporting to the hospital. Germantown Fire Department is equipped with 3 ambulances, 2 of which are Paramedic ambulances. Each of the three shifts has five personnel, three of which are Paramedics.

The Germantown Fire Department service area for EMS is 34.5 square miles and covers 8 miles of Interstate 41. GFD responded to 2,109 calls for service in 2020, with approximately 1700 of the calls for service being EMS.